Prevalence and Associated Factors a Systematic Review and Meta Analysis

April 16, 2022 Post a Comment

doi: 10.3389/fnagi.2021.755926. eCollection 2021.

Prevalence and Associated Chance Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis

Affiliations

PMID: 35153714
PMCID: PMC8832102
DOI: 10.3389/fnagi.2021.755926

Gratis PMC article

Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis

Tao Zhang et al. Front Aging Neurosci. 2022 .

Gratuitous PMC commodity

Abstract

Objective: Currently, the prevalence of CF (Cognitive Frailty) is not very clear, and the relationship betwixt CF and its associated take a chance factors has non been accurately evaluated. Therefore, it is necessary to comport a systematic review and meta-assay further to sympathize CF's prevalence and associated factors.

Methods: Embase, PubMed, Web of Scientific discipline, Ovid, and Cochrane were systematically searched for articles exploring the prevalence of CF, the deadline of searching engagement was upwards to March 2021. For the prevalence of CF, the events of CF and the total number of patients in every included study were extracted to guess the prevalence of CF. For associated factors of CF, Odds Ratios (ORs) with (corresponding) 95% confidence intervals (CIs) were used for estimations.

Results: Firstly, the estimated prevalence of CF I (Cognitive Frailty in the model I) was 16%, 95% CI (0.13-0.xix), and the estimated prevalence of CF Two (Cognitive Frailty in model Two) was 6%, 95% CI (0.05-0.07). Secondly, both lower engagement in activities and age were calculated to be independent risk factors of CF, and the OR (95% CI) was 3.31 (two.28-iv.81) and 1.ten (i.04-1.16), respectively. Finally, low was also a prominent risk cistron of CF, with the overall OR (95% CI) as 1.57 (i.32-one.87).

Conclusion: CF was a high prevalence in customs older. The various cess scales and the different cutoff values of diagnostic criteria would affect the prevalence of CF. Lower engagement in activities, age, and depression was the risky factor of CF.

Systematic review registration: http://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42019121369.

Keywords: associated gene; cognitive; cognitive frailty (CF); frailty; prevalence.

Conflict of interest statement

The authors declare that the enquiry was conducted in the absence of whatsoever commercial or fiscal relationships that could be construed as a potential conflict of interest.

Figures

**Figure ane**
The PRISMA diagram of the study selection.

**Effigy two**
The forest plot pooled the prevalence of CF I.

**Figure 3**
The woods plot pooled the prevalence of CF II.

**Figure 4**
The forest plot illustrated the associated chance factors about CF.

**Effigy 5**
The wood plot illustrated the OR for diverse depression assessment scales estimating risk factor of CF.

**Figure half-dozen**
Funnel plots of non-parametric trim-and-fill method regards the OR for diverse depression assessment scales estimating run a risk factor of CF.

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